Lee, Seung-Ho; Hwang, Sun-Mi; Kang, Do-Hyung; Yang, Hyun-Jeong
Medicine
2019May ; 98 ( 19 ) :e15574.
PMID : 31083232
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Lee, Seung-Ho -
Hwang, Sun-Mi -
Kang, Do-Hyung -
Yang, Hyun-Jeong -
ABSTRACT
BACKGROUND: Hypertension and type 2 diabetes are chronic diseases, which generally require lifetime care. Meditation and yoga can be complementary to pharmacological therapies according to the scientific evidences so far. Brain education-based meditation (BEM) is a technique, which has been known to change brain structure, psychology, and physiology of healthy adult participants. This randomized, nonblinded pilot trial aimed to examine whether BEM affects the conditions of patients with hypertension and/or type 2 diabetes compared with health education classes.
METHODS: We randomly allocated 48 patients with hypertension and/or type 2 diabetes to BEM (n?=?24) or health education (n?=?24) classes in the Ulsan Junggu Public Health Center in Korea, where the classes were run during the same period and explored the impact of 8-week practice on the serum glutamic-oxaloacetic transaminase, serum glutamic pyruvic transaminase, gamma glutamyl transpeptidase, creatinine, high-density lipoprotein cholesterol, and low-density lipoprotein (LDL) cholesterol. Total RNA was extracted to examine inflammatory gene expressions from the whole blood using PAXgene blood RNA System. In addition, self-reports on mental/physical health were evaluated. The Student's t test, chi-squared test, and analysis of covariance were used for statistical analysis.
RESULTS: The number of people who participated until the completion of the study was 14 in the control and 21 in the BEM group. After 8 weeks, LDL cholesterol level was significantly decreased in the BEM group after the intervention (13.82?mg/dL reduction, P?
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