Choi, Yangsean; Jung, So Lyung; Bae, Ja-Sung; Lee, So-Hee; Jung, Chan-Kwon; Jang, Jinhee; Shin, Na-Young; Choi, Hyun Seok; Ahn, Kook-Jin; Kim, Bum-Soo
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
2019Mar ; 16 ( 5 ) :1-9.
PMID : 30836037
ÀúÀÚ »ó¼¼Á¤º¸
Choi, Yangsean - a Department of Radiology , The Catholic University of Korea College of Medicine, Seoul St. Mary's Hospital , Seoul , Korea.
Jung, So Lyung - a Department of Radiology , The Catholic University of Korea College of Medicine, Seoul St. Mary's Hospital , Seoul , Korea.
Bae, Ja-Sung - b Department of Thyroid Surgery , The Catholic University of Korea College of Medicine, Seoul St. Mary's Hospital , Seoul , Korea.
Lee, So-Hee - b Department of Thyroid Surgery , The Catholic University of Korea College of Medicine, Seoul St. Mary's Hospital , Seoul , Korea.
Jung, Chan-Kwon - c Department of Pathology , The Catholic University of Korea College of Medicine, Seoul St. Mary's Hospital , Seoul , Korea.
Jang, Jinhee - a Department of Radiology , The Catholic University of Korea College of Medicine, Seoul St. Mary's Hospital , Seoul , Korea.
Shin, Na-Young - a Department of Radiology , The Catholic University of Korea College of Medicine, Seoul St. Mary's Hospital , Seoul , Korea.
Choi, Hyun Seok - a Department of Radiology , The Catholic University of Korea College of Medicine, Seoul St. Mary's Hospital , Seoul , Korea.
Ahn, Kook-Jin - a Department of Radiology , The Catholic University of Korea College of Medicine, Seoul St. Mary's Hospital , Seoul , Korea.
Kim, Bum-Soo - a Department of Radiology , The Catholic University of Korea College of Medicine, Seoul St. Mary's Hospital , Seoul , Korea.
ABSTRACT
PURPOSE: To compare the efficacy and complication rates of radiofrequency ablation (RFA) and repeat surgery in the treatment of locally recurrent thyroid cancers. MATERIALS AND
METHODS: A total of 221 patients with locally recurrent thyroid cancers who underwent either RFA (n?=?96) or repeat surgery (n?=?125) between March 2008 and March 2017 were retrospectively enrolled (range of follow-up, 1-10?years). Each cohort consisted of 70 patients after propensity score adjustment. Patients with more than three recurrent lesions were excluded. The primary and secondary end points were recurrence-free survival and complication rates, respectively. Recurrence-free survival curves were compared via the log-rank test. The complications-voice changes, hypocalcemia, and immediate procedural complications-were compared between the groups. In addition, pretreatment serum thyroglobulin (T(g)) levels and those at the last follow-up were also compared between the two groups to examine therapeutic efficacy.
RESULTS: After propensity score matching, both groups showed no significant differences in baseline characteristics. The recurrence-free survival rates were comparable between the RFA and surgery groups (p?=?.2). There were no significant differences in mean serum T(g) levels and their mean decrease after treatment between the groups (p?=?.891 and p?=?.963, respectively). Immediate procedural complications and voice changes also showed no significant between-group differences (p?=?.316, p?=?.084, respectively). Hypocalcemia occurred only in the repeat surgery group (n?=?18). Overall complications were significantly more frequent in the repeat surgery group (RFA, n?=?7; surgery, n?=?27; p?
keyword
Thyroid; radiofrequency ablation; recurrent thyroid cancer; thermal ablation; ultrasound
¸µÅ©