Longer-term outcomes of radiofrequency ablation for locally recurrent papillary thyroid cancer.

Chung, Sae Rom; Baek, Jung Hwan; Choi, Young Jun; Lee, Jeong Hyun
European radiology
2019Feb ; 83 ( 3 ) :.
저자 상세정보
Chung, Sae Rom - Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.
Baek, Jung Hwan - Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea. radbaek@naver.com.
Choi, Young Jun - Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.
Lee, Jeong Hyun - Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.
ABSTRACT
OBJECTIVES: The purpose of this study was to evaluate the longer-term efficacy of ultrasound (US)-guided radiofrequency ablation (RFA) for treating locally recurrent papillary thyroid cancer (PTC).

METHODS: We retrospectively reviewed 29 patients who underwent RFA for 46 recurrent PTC between September 2008 and April 2012 and were subsequently followed up for at least 5?years. Follow-up included size change on US and thyroglobulin (Tg) level at 1, 3, 6, and 12?months and every 6-12?months thereafter. Any complications were reported during follow-up.

RESULTS: The mean follow-up duration after RFA was 80?짹?17.3?months (range, 60-114?months). Tumor volume decreased significantly, from 0.25?짹?0.42?mL before ablation to 0.01?짹?0.08?mL at the final evaluation (p?
CONCLUSIONS: RFA seems to be an effective minimally invasive therapy for the treatment of locally recurrent PTC even in the longer-term period. KEY POINTS: ? RFA is an effective local control treatment option for recurrent PTCs even in the longer-term period with mean tumor VRR of 99.5% and the complete disappearance of the treated tumors in 91.3%. ? The mean serum Tg level decreased significantly after RFA and biochemical remission rate was 51.7%. ? No delayed complication after RFA for local recurrent PTC.
keyword
Ablation techniques; Recurrence; Thyroid cancer; Treatment outcome; Ultrasonography
링크

주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
RFA is an effective local control treatment option for recurrent PTCs even in the longer-term period with mean tumor VRR of 99.5% and the complete disappearance of the treated tumors in 91.3%.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
DOI
10.1007/s00330-019-06063-5
KCD코드
ICD 03
건강보험코드