Chung, Sae Rom; Baek, Jung Hwan; Choi, Young Jun; Lee, Jeong Hyun
European radiology
2019Feb ; 83 ( 3 ) :.
PMID : 30805701
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Chung, Sae Rom - Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.
Baek, Jung Hwan - Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea. radbaek@naver.com.
Choi, Young Jun - Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.
Lee, Jeong Hyun - Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.
ABSTRACT
OBJECTIVES: The purpose of this study was to evaluate the longer-term efficacy of ultrasound (US)-guided radiofrequency ablation (RFA) for treating locally recurrent papillary thyroid cancer (PTC).
METHODS: We retrospectively reviewed 29 patients who underwent RFA for 46 recurrent PTC between September 2008 and April 2012 and were subsequently followed up for at least 5?years. Follow-up included size change on US and thyroglobulin (Tg) level at 1, 3, 6, and 12?months and every 6-12?months thereafter. Any complications were reported during follow-up.
RESULTS: The mean follow-up duration after RFA was 80?±?17.3?months (range, 60-114?months). Tumor volume decreased significantly, from 0.25?±?0.42?mL before ablation to 0.01?±?0.08?mL at the final evaluation (p?
CONCLUSIONS: RFA seems to be an effective minimally invasive therapy for the treatment of locally recurrent PTC even in the longer-term period. KEY POINTS: ? RFA is an effective local control treatment option for recurrent PTCs even in the longer-term period with mean tumor VRR of 99.5% and the complete disappearance of the treated tumors in 91.3%. ? The mean serum Tg level decreased significantly after RFA and biochemical remission rate was 51.7%. ? No delayed complication after RFA for local recurrent PTC.
keyword
Ablation techniques; Recurrence; Thyroid cancer; Treatment outcome; Ultrasonography
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