Kim, Jung-Wook; Jang, Jae-Young; Park, Yoo Min; Shim, Jae-Jun; Chang, Young Woon
Surgical endoscopy
2019Mar ; 33 ( 3 ) :794-801.
PMID : 30014330
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Kim, Jung-Wook - Division of Gastroenterology, Department of Internal Medicine, College of Medicine, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemoongu, Seoul, 02447, Republic of Korea.
Jang, Jae-Young - Division of Gastroenterology, Department of Internal Medicine, College of Medicine, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemoongu, Seoul, 02447, Republic of Korea. jyjang@khu.ac.kr.
Park, Yoo Min - Department of Medicine, Graduate School, Kyung Hee University, Seoul, Republic of Korea.
Shim, Jae-Jun - Division of Gastroenterology, Department of Internal Medicine, College of Medicine, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemoongu, Seoul, 02447, Republic of Korea.
Chang, Young Woon - Division of Gastroenterology, Department of Internal Medicine, College of Medicine, Kyung Hee University, 26, Kyungheedae-ro, Dongdaemoongu, Seoul, 02447, Republic of Korea.
ABSTRACT
BACKGROUND: Endoscopic submucosal dissection (ESD) is widely used for large superficial gastrointestinal tumors. Epigastric pain is a frequent complication of ESD. However, little is known about its incidence and associated factors. This study evaluated pain incidence and characteristics of patients with pain after gastric ESD.
METHODS: We retrospectively analyzed a prospectively collected registry of clinical, endoscopic, and pathologic results of patients who underwent ESD for gastric adenoma or cancer from January 2010 to December 2015. A Visual Analogue Scale (VAS) was used to assess pain immediately after, and 2, 12, and 24?h after ESD. The primary outcome was the use of painkillers (VAS score?>?4). Analyzed data included age, sex, pathology, specimen and tumor size, procedure time, and tumor location.
RESULTS: Of 1226 patients, 461 (36.4%) needed a painkiller at least once after ESD (pain group). Compared with the no pain group, the pain group had more females, less alcohol consumption, larger tumor and specimen size, and more antral lesions. In multivariate analysis, female sex (OR 1.559, 95% CI 1.217-1.996, p?
keyword
Complication; Endoscopic submucosal dissection; Pain; Stomach
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