Radiofrequency ablation of primary thyroid carcinoma: efficacy according to the types of thyroid carcinoma.

Jeong, So Yeong; Baek, Jung Hwan; Choi, Young Jun; Chung, Sae Rom; Sung, Tae Yon; Kim, Won Gu; Kim, Tae Yong; Lee, Jeong Hyun
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
2018Aug ; 34 ( 5 ) :611-616.
저자 상세정보
Jeong, So Yeong - a Department of Radiology and Research Institute of Radiology , Asan Medical Center, University of Ulsan College of Medicine , Seoul , Korea.
Baek, Jung Hwan - a Department of Radiology and Research Institute of Radiology , Asan Medical Center, University of Ulsan College of Medicine , Seoul , Korea.
Choi, Young Jun - a Department of Radiology and Research Institute of Radiology , Asan Medical Center, University of Ulsan College of Medicine , Seoul , Korea.
Chung, Sae Rom - a Department of Radiology and Research Institute of Radiology , Asan Medical Center, University of Ulsan College of Medicine , Seoul , Korea.
Sung, Tae Yon - b Department of Surgery , Asan Medical Center, University of Ulsan College of Medicine , Seoul , Korea.
Kim, Won Gu - c Department of Internal Medicine , Asan Medical Center, University of Ulsan College of Medicine , Seoul , Korea.
Kim, Tae Yong - c Department of Internal Medicine , Asan Medical Center, University of Ulsan College of Medicine , Seoul , Korea.
Lee, Jeong Hyun - a Department of Radiology and Research Institute of Radiology , Asan Medical Center, University of Ulsan College of Medicine , Seoul , Korea.
ABSTRACT
OBJECTIVE: To evaluate the efficacy of ultrasound (US)-guided radiofrequency ablation (RFA) according to the types of thyroid carcinoma, particularly in patients with a high-surgical risk. MATERIALS AND

METHODS: Eight patients with nine tumours of pathologically proven papillary and anaplastic carcinoma were treated by US-guided RFA. Patients with primary thyroid carcinoma were divided into three groups; group (1) Anaplastic carcinoma, group (2) papillary macrocarcinoma, and group (3) papillary microcarcinoma. We evaluated changes in clinical symptoms, tumour volume and local tumour recurrence/metastasis after RFA. Patients were followed up at 1, 6 and 12 months and annually thereafter.

RESULTS: Among nine tumours, one anaplastic carcinoma was treated three times and the other anaplastic carcinoma and one papillary macrocarcinoma were treated twice. Group 3 were treated once. The initial mean tumour volume was 107.9?짹?78.6 (with neck bulging), 126.9 (with neck bulging) and 0.16?짹?0.08?mL (without cosmetic or symptomatic problems) in groups 1-3, respectively. Group 1 showed no improvement in clinical symptoms or neck bulging after RFA, whereas group 2 demonstrated a decreased tumour volume measuring 0.7?mL with improved neck bulging. In group 3, mean volume decreased measuring 0.07?짹?0.12?mL. No local tumour recurrence or metastatic lesion was detected during the mean follow-up of 19.3 months in papillary carcinomas. No major complications were encountered.

CONCLUSIONS: In patients with primary thyroid carcinoma, RFA achieved excellent local tumour control for papillary macro- and microcarcinoma; however, its clinical effect on anaplastic carcinoma was questionable.
keyword
Radiofrequency ablation; thyroid cancer; ultrasonography
링크

주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
RFA achieved excellent local tumour control for papillary macro- and micro-carcinoma in primary thyroid carcinoma.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
DOI
https://doi.org/10.1080/02656736.2018.1427288
KCD코드
ICD 03
건강보험코드