Magnetic resonance imaging for detection of parametrial invasion in cervical cancer: An updated systematic review and meta-analysis of the literature between 2012 and 2016.

Woo, Sungmin; Suh, Chong Hyun; Kim, Sang Youn; Cho, Jeong Yeon; Kim, Seung Hyup
European radiology
2017Jul ; 54 ( 1 ) :.
PMID : 28726120
ÀúÀÚ »ó¼¼Á¤º¸
Woo, Sungmin -
Suh, Chong Hyun -
Kim, Sang Youn -
Cho, Jeong Yeon -
Kim, Seung Hyup -
ABSTRACT
OBJECTIVE: To review the diagnostic performance?of MRI for detection of parametrial invasion (PMI) in cervical cancer patients.

METHODS: MEDLINE and EMBASE databases were searched for studies providing diagnostic performance of MRI for detecting PMI in patients with cervical cancer. Studies published between 2012 and 2016 using surgico-pathological results as reference standard were included. Study quality was evaluated using QUADAS-2. Sensitivity and specificity of all studies were calculated. Results were pooled and plotted in a hierarchical summary receiver operating characteristic plot. Meta-regression and subgroup analyses were performed.

RESULTS: Fourteen studies (1,028 patients) were included. Study quality was generally moderate. Pooled sensitivity was 0.76 (95% CI 0.67-0.84) and specificity was?0.94 (95% CI 0.91-0.95). The possibility of heterogeneity was considered low: Cochran's Q-test (p?=?0.471), Tau(2) (0.240), Higgins I(2) (0%). With meta-regression analysis, magnet strength, use of DWI, and antispasmodic drugs were significant factors affecting heterogeneity (p?
CONCLUSIONS: MRI shows good performance for detection of PMI in cervical cancer. Using 3-T scanners and DWI may improve diagnostic performance. KEY POINTS: ? MRI shows good performance for detection of parametrial invasion in cervical cancer. ? Subgroup of studies using only radical hysterectomy showed consistent results. ? Using 3-Tesla scanners and diffusion-weighted imaging may improve diagnostic performance.
Cervical cancer; Magnetic resonance imaging; Meta-analysis; Parametrial invasion; Systemic review
¸µÅ©

ÁÖÁ¦ÄÚµå
ÁÖÁ¦¸í(Target field)
¿¬±¸´ë»ó(Population)
¿¬±¸Âü¿©(Sample size)
´ë»ó¼ºº°(Gender)
Áúº´Æ¯¼º(Condition Category)
¿¬±¸È¯°æ(Setting)
¿¬±¸¼³°è(Study Design)
¿¬±¸±â°£(Period)
ÁßÀç¹æ¹ý(Intervention Type)
ÁßÀç¸íĪ(Intervention Name)
Å°¿öµå(Keyword)
À¯È¿¼º°á°ú(Recomendation)
MRI shows good performance for detection of parametrial invasion in cervical cancer.
¿¬±¸ºñÁö¿ø(Fund Source)
±Ù°Å¼öÁØÆò°¡(Evidence Hierarchy)
ÃâÆdz⵵(Year)
Âü¿©ÀúÀÚ¼ö(Authors)
´ëÇ¥ÀúÀÚ
DOI
10.1007/s00330-017-4958-x.
KCDÄÚµå
ICD 03
°Ç°­º¸ÇèÄÚµå