Radiofrequency ablation of small follicular neoplasms: initial clinical outcomes.

Ha, Su Min; Sung, Jin Yong; Baek, Jung Hwan; Na, Dong Gyu; Kim, Ji-Hoon; Yoo, Hyunju; Lee, Ducky; Whan Choi, Dong
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
2017May ; 103 ( 21 ) :1-7.
저자 상세정보
Ha, Su Min -
Sung, Jin Yong -
Baek, Jung Hwan -
Na, Dong Gyu -
Kim, Ji-Hoon -
Yoo, Hyunju -
Lee, Ducky -
Whan Choi, Dong -
ABSTRACT
BACKGROUND: In thyroid gland, radiofrequency ablation (RFA) has been applied to both recurrent cancers and benign nodules, although, according to the American Thyroid Association (ATA) and the Korean Society of Thyroid Radiology (KSThR) guidelines, surgery is the first-line treatment for follicular neoplasm. However, it has been argued that follicular neoplasm with lower risk of malignancy can be managed by close follow-up. In this study, we evaluated the effectiveness of RFA of small follicular neoplasms, examining reductions in volume and related clinical problems, and making observations over long-term follow-up.

METHODS: We evaluated 10 follicular neoplasms in 10 patients who were treated with RF ablation between 2009 and 2011. A RF generator and an 18-gauge internally cooled electrode were used to perform complete ablation of the whole nodules. Changes in nodules or ablated zones on follow-up ultrasound, and complications during and after RF ablation were evaluated.

RESULTS: The mean follow-up period was 66.4?짹?5.1?months (range: 60-76?months). In eight patients, single session of RF ablation was sufficient, while two patients required two sessions. There was a significant reduction in the mean volume (99.5?짹?1.0%) of lesions, with eight ablated lesions (8/10, 80%) disappearing completely on follow-up. No recurrences were found in any ablated zones at last follow-up. Transient mild neck pain (n?=?6) occurred during the procedure without requiring any medication. CONCLUSION: In addition to active surveillance, RF ablation may be an effective and safe alternative for the management of patients with small (<2?cm) follicular neoplasm suspected on thyroid biopsy and who strongly refuse surgery.
Thermal ablation; radiofrequency/microwave; thyroid neoplasm; ultrasound.
링크

주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
In eight patients, single session of RF ablation was sufficient, while two patients required two sessions. There was a significant reduction in the mean volume (99.5 ± 1.0%) of lesions, with eight ablated lesions (8/10, 80%) disappearing completely on follow-up.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
DOI
10.1080/02656736.2017.1331268
KCD코드
ICD 03
건강보험코드