KCTBASE

Age-Period-Cohort Analysis of Liver Cancer Mortality in Korea.

Park, Jihwan; Jee, Yon Ho

Asian Pacific journal of cancer prevention : APJCP
2015NA ; 16 ( 18 ) :8589-94.

PMID : 26745121

저자 상세정보

Park, Jihwan -
Jee, Yon Ho -

ABSTRACT

BACKGROUND: Liver cancer is one of the most common causes of death in the world. In Korea, hepatitis B virus (HBV) is a major risk factor for liver cancer but infection rates have been declining since the implementation of the national vaccination program. In this study, we examined the secular trends in liver cancer mortality to distinguish the effects of age, time period, and birth cohort. MATERIALS AND

METHODS: Data for the annual number of liver cancer deaths in Korean adults (30 years and older) were obtained from the Korean Statistical Information Service for the period from 1984-2013. Joinpoint regression analysis was used to study the shapes of and to detect the changes in mortality trends. Also, an age-period-cohort model was designed to study the effect of each age, period, and birth cohort on liver cancer mortality.

RESULTS: For both men and women, the age-standardized mortality rate for liver cancer increased from 1984 to 1993 and decreased thereafter. The highest liver cancer mortality rate has shifted to an older age group in recent years. Within the same birth cohort group, the mortality rate of older age groups has been higher than in the younger age groups. Age-period-cohort analysis showed an association with a high mortality rate in the older age group and in recent years, whereas a decreasing mortality rate were observed in the younger birth cohort.

CONCLUSIONS: This study confirmed a decreasing trend in liver cancer mortality among Korean men and women after 1993. The trends in mortality rate may be mainly attributed to cohort effects.

Liver cancer - mortality - trends - age - time period - birth cohort - Korea

링크

PubMed

주제코드

주제명(Target field)

연구대상(Population)

연구참여(Sample size)

대상성별(Gender)

질병특성(Condition Category)

연구환경(Setting)

연구설계(Study Design)

연구기간(Period)

중재방법(Intervention Type)

중재명칭(Intervention Name)

키워드(Keyword)

유효성결과(Recomendation)

In this study, the mortality from HCC still remained high in the older population and even increased in the population aged 80 years or older; a decreasing trend in liver cancer mortality among Korean men and women after 1993.

연구비지원(Fund Source)

근거수준평가(Evidence Hierarchy)

출판년도(Year)

참여저자수(Authors)

대표저자

DOI

http://dx.doi.org/10.7314

KCD코드

ICD 03

건강보험코드