Kim, Sun-Young; Oh, Mi-Ra; Kim, Min-Gul; Chae, Han-Jeoung; Chae, Soo-Wan
BMC complementary and alternative medicine
2015NA ; 15 ( 3 ) :338.
PMID : 26408319
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Kim, Sun-Young -
Oh, Mi-Ra -
Kim, Min-Gul -
Chae, Han-Jeoung -
Chae, Soo-Wan -
ABSTRACT
BACKGROUND: Obesity is a major health problem. A food field research that has recently aroused considerable interest is the potential of natural products to counteract obesity. Yerba Mate may be helpful in reducing body weight and fat. The aim of this study was to investigate the efficacy and safety of Yerba Mate supplementation in Korean subjects with obesity.
METHODS: A randomized, double-blind, placebo-controlled trial was conducted. Subjects with obesity (body mass index (BMI)???25 but?
RESULTS: During 12 weeks of Yerba Mate supplementation, decreases in body fat mass (P?=?0.036) and percent body fat (P?=?0.030) compared to the placebo group were statistically significant. WHR was significantly decreased (P?=?0.004) in the Yerba Mate group compared to the placebo group. No clinically significant changes in any safety parameters were observed.
CONCLUSIONS: Yerba Mate supplementation decreased body fat mass, percent body fat and WHR. Yerba Mate was a potent anti-obesity reagent that did not produce significant adverse effects. These results suggested that Yerba Mate supplementation may be effective for treating obese individuals. TRIAL REGISTRATION: ClinicalTrials.gov: (NCT01778257).
Yerba Mate, Ilex paraguariensis, Obesity, Clinical trials
MESH
Adipose Tissue/drug effects, Adult, Body Composition/drug effects, Body Weight/drug effects, Capsules, Dietary Supplements, Double-Blind Method, Female, Humans, *Ilex paraguariensis, Male, Middle Aged, Obesity/*drug therapy, *Phytotherapy, Plant Extracts/pharmacology/therapeutic use, Waist-Hip Ratio
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