The Effects of Combined Exercise on Health-Related Fitness, Endotoxin, and Immune Function of Postmenopausal Women with Abdominal Obesity.

Park, Sung-Mo; Kwak, Yi-Sub; Ji, Jin-Goo
Journal of immunology research
2015NA ; 2015 ( 1 ) :830567.
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Park, Sung-Mo - Department of Physical Education, Dong-Eui University, 995 Eomgwangno, Busanjin-gu, Busan 614-714, Republic of Korea.
Kwak, Yi-Sub - Department of Physical Education, Dong-Eui University, 995 Eomgwangno, Busanjin-gu, Busan 614-714, Republic of Korea.
Ji, Jin-Goo - Department of Physical Education, Dong-Eui University, 995 Eomgwangno, Busanjin-gu, Busan 614-714, Republic of Korea.
ABSTRACT
This study was conducted to examine the effects of combined exercise on health-related fitness, endotoxin concentrations, and immune functions of postmenopausal women with abdominal obesity. 20 voluntary participants were recruited and they were randomly allocated to the combined exercise group (n = 10) or the control group (n = 10). Visceral obesity was defined as a visceral-to-subcutaneous fat ratio ??0.4 based on computed tomography (CT) results. Body composition, exercise stress testing, fitness measurement, CT scan, and blood variables were analyzed to elucidate the effects of combined exercise. The SPSS Statistics 18.0 program was used to calculate means and standard deviations for all variables. Significant differences between the exercise group and control group were determined with 2-way ANOVA and paired t-tests. The exercise group's abdominal obesity was mitigated due to visceral fat reduction; grip strength, push-ups, and oxygen uptake per weight improved; and HDL-C and IgA level also increased, while TNF-α, CD14, and endotoxin levels decreased. Lowered TNF-α after exercise might have an important role in the obesity reduction. Therefore, we can conclude that combined exercise is effective in mitigating abdominal obesity, preventing metabolic diseases, and enhancing immune function.
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MESH
Adipose Tissue/immunology/metabolism/physiology, Antigens, CD14/immunology, Body Composition/immunology/physiology, Body Mass Index, Endotoxins/metabolism, Exercise/*physiology, Female, Humans, Immunoglobulin A/immunology, Middle Aged, Obesity, Abdominal/*immunology/metabolism/*physiopathology, Physical Fitness/*physiology, Postmenopause/*immunology/metabolism/*physiology, Tumor Necrosis Factor-alpha/immunology
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In the exercise group, visceral fat and the visceral to subcutaneous fat ratio (both p < 0.01) decreased significantly compared to preprogram values. Visceral fat (F = 7.619, p < 0.01) and the visceral to subcutaneous fat ratio (F = 29.894, p < 0.001) changed significantly over time and between groups.
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DOI
10.1155/2015/830567
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ICD 03
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