Efficacy and safety of radiofrequency ablation for treating locoregional recurrence from papillary thyroid cancer.

Lim, Hyun Kyung; Baek, Jung Hwan; Lee, Jeong Hyun; Kim, Won Bae; Kim, Tae Yong; Shong, Young Kee; Hong, Suck Joon
European radiology
2015Jan ; 25 ( 1 ) :163-70.
저자 상세정보
Lim, Hyun Kyung -
Baek, Jung Hwan -
Lee, Jeong Hyun -
Kim, Won Bae -
Kim, Tae Yong -
Shong, Young Kee -
Hong, Suck Joon -
ABSTRACT
OBJECTIVES: To assess the efficacy and safety of ultrasound- (US) guided radiofrequency ablation (RFA) for controlling locoregional recurrent papillary thyroid cancer (PTC) in a large patient population.

METHODS: We included patients who had undergone RFA for locoregional recurrent PTC between September 2008 and April 2012 who fulfilled the following criteria: no metastasis beyond the neck; not more than four tumours; confirmed recurrence by US-guided fine needle aspiration biopsy or thyroglobulin measurement of needle washouts; more than a six-month follow-up period; and surgery not feasible or was refused by the patient.

RESULTS: Sixty-one recurrent tumours in 39 patients were included. The mean follow-up duration was 26.4 짹 13.7 months. Tumour volume decreased significantly from 0.20 짹 0.35 ml before ablation to 0.02 짹 0.11 ml (P
CONCLUSIONS: RFA can effectively control locoregional recurrent PTC without life-threatening complications; therefore, RFA may replace "berry picking surgery" in selected patients. KEY POINTS: ? RFA for recurrent PTC achieved a volume reduction ratio of 95.1 짹 12.3% ? Eighty-two percent (50/61) of recurrent PTC completely disappeared after RFA ? The mean serum thyroglobulin level decreased significantly (P =?.001) after RFA ? RFA may replace "berry picking surgery" for recurrent PTC.
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MESH
Adult, Aged, Aged, 80 and over, Biopsy, Fine-Needle, Carcinoma/pathology/*surgery/ultrasonography, Catheter Ablation/*methods, Female, Humans, Male, Middle Aged, Neoplasm Recurrence, Local/pathology/*surgery/ultrasonography, Retrospective Studies, Surgery, Computer-Assisted/*methods, Thyroid Neoplasms/pathology/*surgery/ultrasonography, Treatment Outcome, Young Adult
링크

주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
Tumour volume decreased significantly from 0.20 +/- 0.35 ml before ablation to 0.02 +/- 0.11 ml (P < .001), with a mean volume reduction ratio of 95.1 +/- 12.3%. Fifty tumours (82.0%) completely disappeared.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
DOI
10.1007/s00330-014-3405-5
KCD코드
ICD 03
건강보험코드