Usefulness of two-stage ethanol ablation in the treatment of benign predominantly cystic thyroid nodules.

Kim, Dong Wook
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
2014Jun ; 20 ( 6 ) :548-55.
저자 상세정보
Kim, Dong Wook - Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan, South Korea.
ABSTRACT
OBJECTIVE: The management of benign predominantly cystic thyroid nodules (PCTNs) differs depending on the institution or practitioner. This study aimed to assess the efficacy of two-stage ultrasound (US)-guided ethanol ablation (EA) in treating PCTNs.

METHODS: Over a 1-year period, two-stage EA was performed on benign PCTNs for 25 patients. After EA, each patient was followed up with thyroid US. The two-stage EA treatment consisted of an initial EA for the cystic component of the PCTN and subsequent treatment for the remaining solid component, if needed.

RESULTS: All 25 patients underwent EA for the cystic component of a PCTN and showed complete collapse of the cystic component on the follow-up US. Twenty patients were subsequently treated with one or more EA sessions because of the presence of a vascularized solid component, whereas 5 patients underwent no additional EA sessions because no vascularized solid component was detected on follow-up US. Of the 20 patients who underwent additional EA for a remaining solid component, complete ablation (n = 9), incomplete ablation (n = 7), and no response (n = 4) were observed on follow-up US. Of the 7 patients with incomplete ablation despite repeated EA, only 4 underwent radiofrequency ablation, and they showed complete ablation on follow-up US. CONCLUSION: Two-stage EA may be useful for the treatment of benign PCTNs.
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링크

주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
Of the 20 patients who underwent additional EA for a remaining solid component, complete ablation (n = 9), incomplete ablation (n = 7), and no response (n = 4) were observed on follow-up US. Of the 7 patients with incomplete ablation despite repeated EA, only 4 underwent radiofrequency ablation, and they showed complete ablation on follow-up US.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
DOI
10.4158/EP13458.OR.
KCD코드
ICD 03
건강보험코드