Lim, Hyun Kyung; Lee, Jeong Hyun; Ha, Eun Ju; Sung, Jin Young; Kim, Jae Kyun; Baek, Jung Hwan
European radiology
2013Apr ; 23 ( 4 ) :1044-9.
PMID : 23096937
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Lim, Hyun Kyung -
Lee, Jeong Hyun -
Ha, Eun Ju -
Sung, Jin Young -
Kim, Jae Kyun -
Baek, Jung Hwan -
ABSTRACT
OBJECTIVES: To evaluate the clinical outcomes and safety of radiofrequency (RF) ablation for benign non-functioning thyroid nodules over a 4-year follow-up.
METHODS: We evaluated 126 benign non-functioning thyroid nodules of 111 patients treated with RF ablation and followed-up more than 3 years. RF ablation was performed using the Cool-Tip RF system and an internally cooled electrode. Nodule volume and cosmetic and symptom scores were evaluated before treatment and during follow-up. Complications and factors related to efficacy were evaluated.
RESULTS: The mean follow-up duration was 49.4?±?13.6 months. Thyroid nodule volume decreased significantly, from 9.8?±?8.5 ml before ablation to 0.9?±?3.3 ml (P?0.001) at final evaluation: a mean volume reduction of 93.4?±?11.7 %. The mean cosmetic (P?0.001) and symptom scores (P?0.001) improved significantly. Factors related to efficacy were initial solidity and volume. The overall recurrence rate was 5.6 % (7/126). The overall complication rate was 3.6 % (4/111).
CONCLUSIONS: RF ablation was effective in shrinking benign thyroid nodules and in controlling nodule-related problems over a 4-year follow-up. There were no life-threatening complications or sequelae. Therefore, RF ablation can be used as a non-surgical treatment for patients with benign non-functioning thyroid nodules.
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MESH
Adult, Aged, Catheter Ablation/*statistics & numerical data, Female, Follow-Up Studies, Humans, Male, Middle Aged, Prevalence, Republic of Korea/epidemiology, Risk Factors, Thyroid Nodule/*epidemiology/*surgery/ultrasonography, Treatment Outcome, Young Adult
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