Evaluation of four rapid diagnostic tests for the diagnosis of Plasmodium vivax in Korea.

Kim, Kyung Hee; Jang, Jin Woo; Woo, Mi Kyung; Oh, Jun Seo; Han, Eun Taek; Lee, Won Ja; An, Seong Soo A; Lim, Chae Seung
Tropical medicine & international health : TM & IH
2011Nov ; 16 ( 11 ) :1427-31.
저자 상세정보
Kim, Kyung Hee -
Jang, Jin Woo -
Woo, Mi Kyung -
Oh, Jun Seo -
Han, Eun Taek -
Lee, Won Ja -
An, Seong Soo A -
Lim, Chae Seung -
ABSTRACT
OBJECTIVE: To evaluate 4 rapid malaria diagnostic kits (RDTs) in Korea: OptiMAL test, SD BIOLINE Malaria Ag P.f/Pan test, Humasis Malaria P.f/Pan antigen test and CareStart Malaria Pf/Pv Combo test.

METHODS: Hundred malaria patients with Plasmodium vivax (P. vivax) and 100 healthy volunteers were recruited. The results from earlier four RDTs were compared with the reference standard, the Giemsa-stained traditional microscopic diagnosis.

RESULTS: Compared with the reference standard, the sensitivity and specificity for Plasmodium vivax were 92.7 and 100% for SD BIOLINE Malaria Ag P.f/Pan; and 94.6% and 100% for OptiMAL; 95.5% and 100% for both Humasis Malaria P.f/Pan antigen test and CareStart Malaria Pf/Pv Combo test. CONCLUSION: The performances of all four malaria RDT kits were acceptable, although Humasis Malaria P.f/Pan antigen test and CareStart Malaria Pf/Pv Combo test gave superior performances with ROK isolates. CI - ??2011 Blackwell Publishing Ltd.
Plasmodium vivax; OptiMAL; CareStart; sensitivity; specificity; Plasmodium vivax; Optimal; CareStart; sensibilit? sp?ificit? Plasmodium vivax; OptiMAL; CareStart; Sensibilidad; Especificidad
MESH
Adult, Animals, Diagnostic Tests, Routine/*methods, Humans, Malaria, Vivax/*diagnosis, Plasmodium vivax/*isolation & purification, Predictive Value of Tests, Reagent Kits, Diagnostic/*standards, Republic of Korea, Sensitivity and Specificity, Young Adult
링크

주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
All four RDT kits revealed very high sensitivities (range, 92.7?5.5%) and high specificities(range, 100%) for P. vivax. Two new kits, Humasis Malaria P.f/ Pan antigen test and CareStart TM Malaria Pf / Pv Combo test, had a higher sensitivity than other previously developed commercial RDTs, SD BIOLINE Malaria Ag P.f / Pan and OptiMAL, in ROK.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
DOI
10.1111/j.1365-3156.2011.02846.x.
KCD코드
ICD 03
건강보험코드