A pilot study of capsule endoscopy for the diagnosis of radiation enteritis.

Kim, Hee Man; Kim, Yoon Jae; Kim, Hong Jeong; Park, Seung Woo; Bang, Seungmin; Song, Si Young
Hepato-gastroenterology
2011Mar ; 58 ( 106 ) :459-64.
저자 상세정보
Kim, Hee Man -
Kim, Yoon Jae -
Kim, Hong Jeong -
Park, Seung Woo -
Bang, Seungmin -
Song, Si Young -
ABSTRACT
BACKGROUND/AIMS: Capsule endoscopy may be a useful diagnostic tool for radiation enteritis in select situations. We conducted this pilot study to test feasibility of capsule endoscopy in the diagnosis of radiation enteritis. METHODOLOGY: Patients who received chemoradiotherapy to treat pancreatic cancer were enrolled. To increase the diagnostic yield of radiation enteritis, capsule endoscopy was performed in patients having anemia or chronic abdominal pain after chemoradiotherapy.

RESULTS: Fifteen patients were enrolled between June 2007 and December 2008. The mean age was 63.4 +/- 8.0 years. The median radiation dose was 5040cGy with range of 4500-5994cGy. The mean total operating time of capsule was 10h 12 min +/- 2h 37 min, and the complete examination rate to the cecum was 93.3%. Nine patients (60%) were suspected to have radiation enteritis, and of these, five (33.3%) had abnormal findings that strongly suggested radiation enteritis. Congested mucosa and erythematous mucosa were the most frequent abnormal lesions. No capsule retention or other complications occurred.

CONCLUSIONS: Capsule endoscopy may safely and effectively diagnose radiation enteritis in patients previously treated with chemoradiotherapy on the upper abdomen, although a larger trial is needed to confirm this.
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MESH
Aged, Capsule Endoscopy/*methods, Enteritis/*diagnosis, Female, Humans, Male, Middle Aged, Pancreatic Neoplasms/*radiotherapy, Pilot Projects, Radiation Injuries/*diagnosis, Radiotherapy/adverse effects
링크

주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
The mean total operating time of capsule was 10h 12 min +/- 2h 37 min, and the complete examination rate to the cecum was 93.3%; Capsule endoscopy may safely and effectively diagnose radiation enteritis.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
DOI
KCD코드
ICD 03
건강보험코드