Inoperable symptomatic recurrent thyroid cancers: preliminary result of radiofrequency ablation.

Park, Ko Woon; Shin, Jung Hee; Han, Boo-Kyung; Ko, Eun Young; Chung, Jae Hoon
Annals of surgical oncology
2011Sep ; 18 ( 9 ) :2564-8.
저자 상세정보
Park, Ko Woon -
Shin, Jung Hee -
Han, Boo-Kyung -
Ko, Eun Young -
Chung, Jae Hoon -
ABSTRACT
PURPOSE: To determine the role of radiofrequency ablation (RFA) in patients with inoperable symptomatic recurrent thyroid cancers. MATERIALS AND

METHODS: Eleven patients with 16 symptomatic recurrent thyroid cancers but ineligible for surgery were prospectively enrolled and underwent ultrasound-guided RFA with local anesthesia in 16 sessions. The mean tumor volume and diameter were 9?ml (range 0.1-34?ml) and 2.9?cm (range 0.7-4.8?cm), respectively. Patients had dysphagia, hoarseness, dyspnea, or a protruding mass due to recurrent tumors. Tumor volume was calculated from follow-up ultrasound, and symptoms were assessed after RFA.

RESULTS: Of 16 sessions, tumor ablation was complete in 6, incomplete in 9, and failed in 1. Incomplete or failed ablation was due to intolerable pain, severe calcified lesion, or tumor encasement of major vessels. Of 15 treated lesions, 13 decreased in volume. Regrowth of treated tumors was observed in 2 lesions. The mean volume reduction was 50.9% (range -9.4 to 96.8%). There were gains for symptom relief for 7 patients (63.6%) with protruding masses (n?=?6) and discomfort due to tracheal compression (n?=?1). The mean follow-up was 6?months (1-14?months). There were no major complications except a patient with skin burn. CONCLUSION: RFA is feasible and safe, and can improve symptoms in the short term.
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MESH
Adenocarcinoma, Follicular/pathology/*therapy, Adult, Aged, Aged, 80 and over, Carcinoma, Papillary/pathology/*therapy, *Catheter Ablation, Female, Follow-Up Studies, Humans, Male, Middle Aged, Neoplasm Recurrence, Local/*pathology/*therapy, Prospective Studies, Survival Rate, Thyroid Neoplasms/pathology/*therapy, Treatment Outcome
링크

주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
US-guided RF procedure for symptomatic inoperable thyroid cancer can decrease tumor volume and provide palliation in selected patients; Of 15 treated lesions, 13 decreased in volume. Regrowth of treated tumors was observed in 2 lesions. The mean volume reduction was 50.9% (range -9.4 to 96.8%). There were gains for symptom relief for 7 patients (63.6%) with protruding masses (n = 6) and discomfort due to tracheal compression (n = 1).
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
DOI
10.1245/s10434-011-1619-1
KCD코드
ICD 03
건강보험코드