Effect of bowel preparation with polyethylene glycol on quality of capsule endoscopy.

Park, Sung Chul; Keum, Bora; Seo, Yeon Seok; Kim, Yong Sik; Jeen, Yoon Tae; Chun, Hoon Jai; Um, Soon Ho; Kim, Chang Duck; Ryu, Ho Sang
Digestive diseases and sciences
2011Jun ; 56 ( 6 ) :1769-75.
저자 상세정보
Park, Sung Chul -
Keum, Bora -
Seo, Yeon Seok -
Kim, Yong Sik -
Jeen, Yoon Tae -
Chun, Hoon Jai -
Um, Soon Ho -
Kim, Chang Duck -
Ryu, Ho Sang -
BACKGROUND AND AIMS: Capsule endoscopy (CE) has the problem that lumen visualization is impaired by bubbles, bile, and debris. The benefits of bowel preparation are still controversial and the best method remains to be determined. The objective of this study was to evaluate the effect of the method of bowel preparation on the quality of visualization and on transit time.

METHODS: The study sample consisted of 68 patients for CE. Patients were randomly allocated to three groups. In group A (n = 23), patients fasted for 12 h before CE. In groups B (n = 20) and C (n = 25), patients received 2 and 4 l of polyethylene glycol (PEG), respectively. Small bowel images were evaluated by use of a cleansing score system. Representative frames were serially selected at 5-min intervals and scored by assessment of two properties (proportion of luminal visibility and extent of obscuration).

RESULTS: The median scores of image quality in groups A, B, and C were 2.26, 2.43, and 2.55 respectively, (P = 0.034). Cecal completion rates, gastric transit time, and small bowel transit time were no different among the three groups. Detection of lesions in groups A, B, and C was 56.5, 65.0, and 68.0%, respectively.

CONCLUSIONS: Bowel preparation with PEG resulted in better image quality than fasting alone. No significant difference was observed between 2 and 4 l. PEG 2 l rather than 4 l may be a useful method of preparation for CE.
Adult, Aged, Capsule Endoscopy/*standards, Cathartics/*pharmacology, Dose-Response Relationship, Drug, Fasting, Female, Gastrointestinal Hemorrhage/diagnosis, Humans, Image Enhancement, Intestine, Small/*pathology, Male, Middle Aged, Polyethylene Glycols/*pharmacology, Premedication/methods

주제명(Target field)
연구참여(Sample size)
질병특성(Condition Category)
연구설계(Study Design)
중재방법(Intervention Type)
중재명칭(Intervention Name)
Bowel preparation with PEG resulted in better image quality than fasting alone.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
ICD 03