Long-term effects of cilostazol on the prevention of macrovascular disease in patients with type 2 diabetes mellitus.

Rhee, Sang Youl; Kim, Young Seol; Chon, Suk; Oh, Seungjoon; Woo, Jeong-Taek; Kim, Sung Woon; Kim, Jin-Woo
Diabetes research and clinical practice
2011Jan ; 91 ( 1 ) :e11-4.
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Rhee, Sang Youl -
Kim, Young Seol -
Chon, Suk -
Oh, Seungjoon -
Woo, Jeong-Taek -
Kim, Sung Woon -
Kim, Jin-Woo -
ABSTRACT
We analyzed the medical records of 884 type 2 DM patients who were taking different antiplatelet agents for more than 2 years. Based on the records, occurrences of cardiovascular events for 10 years were evaluated. The composite disease-free survival rate for cilostazol monotherapy group was similar to aspirin subgroup (p=0.133). CI - 2010 Elsevier Ireland Ltd. All rights reserved.
Diabetes mellitus; Type 2; Cardiovascular diseases; Aspirin; Cilostazol; Prevention
MESH
Aged, Aspirin/therapeutic use, Cardiovascular Diseases/epidemiology/prevention & control, Cerebrovascular Disorders/epidemiology/prevention & control, Diabetes Mellitus, Type 2/*complications/*drug therapy, Diabetic Angiopathies/epidemiology/*prevention & control, Disease-Free Survival, Drug Therapy, Combination, Female, Humans, Male, Medical Records, Middle Aged, Peripheral Arterial Disease/epidemiology/prevention & control, Platelet Aggregation Inhibitors/*therapeutic use, Proportional Hazards Models, Republic of Korea/epidemiology, Retrospective Studies, Tetrazoles/*therapeutic use
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Cilostazol could be an effective treatment option for the primary prevention of CVD in patients with type 2 diabetes; The composite disease-free survival rate for cilostazol monotherapy group was similar to aspirin subgroup (p=0.133).
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DOI
10.1016/j.diabres.2010.09.009
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ICD 03
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