Radiofrequency ablation (RFA) of benign thyroid nodules in patients with incompletely resolved clinical problems after ethanol ablation (EA).

Lee, Jeong Hyun; Kim, Yoon Suk; Lee, Ducky; Choi, Hoon; Yoo, Hyunju; Baek, Jung Hwan
World journal of surgery
2010Jul ; 34 ( 7 ) :1488-93.
저자 상세정보
Lee, Jeong Hyun -
Kim, Yoon Suk -
Lee, Ducky -
Choi, Hoon -
Yoo, Hyunju -
Baek, Jung Hwan -
ABSTRACT
BACKGROUND: Although ethanol ablation (EA) is effective, refractory cases have been reported in 5-25% of patients, with a marked decline in efficacy on subsequent reattempt. The aim of this study was to evaluate the role of radiofrequency ablation (RFA) after EA of benign thyroid nodules in patients with incompletely resolved initial clinical problems.

METHODS: Among 137 patients with 137 benign thyroid nodules who underwent EA, 27 patients (M:F = 5:22; mean age = 38 years, range = 21-60 years) underwent additional RFA if all of the following criteria were fulfilled: (1) complaint of incompletely resolved clinical problems, (2) demonstration of remaining solid component with internal vascularity on 1-month follow-up power Doppler US, and (3) patient desire for additional treatment. After RFA, there was improvement of clinical symptoms and characteristics and volume reduction of the treated nodules as seen on US; complications were evaluated at each follow-up.

RESULTS: The mean follow-up duration was 21.2 months (range = 6-38 months) after RFA. The mean symptom grading score of 10-cm visual analog scale, the mean cosmetic grading score on a 4-point scale, and the mean volume reduction of thyroid nodules were all significantly decreased from those seen before RFA (2.4-1.1, 3.7-1.5, and 4.2-1.1, respectively) (P < 0.05). There were no major complications.

CONCLUSIONS: RFA is an effective and safe method for treating benign thyroid nodules in patients with incompletely resolved clinical problems following EA.
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MESH
Adult, *Catheter Ablation, Cysts/surgery, Ethanol/administration & dosage/therapeutic use, Humans, Injections, Intralesional/methods, Middle Aged, Retreatment, Retrospective Studies, Thyroid Nodule/*surgery/ultrasonography, Treatment Failure, Young Adult
링크

주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
The mean volume reduction of thyroid nodules were all significantly decreased from those seen before RFA (2.4–1.1, 3.7–1.5, and 4.2–1.1, respectively) (P < 0.05).
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
DOI
10.1007/s00268-010-0565-6.
KCD코드
ICD 03
건강보험코드