Radiofrequency ablation of benign thyroid nodules: safety and imaging follow-up in 236 patients.

Jeong, Woo Kyoung; Baek, Jung Hwan; Rhim, Hyunchul; Kim, Yoon Suk; Kwak, Min Sook; Jeong, Hyun Jo; Lee, Ducky
European radiology
2008Jun ; 18 ( 6 ) :1244-50.
저자 상세정보
Jeong, Woo Kyoung -
Baek, Jung Hwan -
Rhim, Hyunchul -
Kim, Yoon Suk -
Kwak, Min Sook -
Jeong, Hyun Jo -
Lee, Ducky -
ABSTRACT
This study evaluated the safety and volume reduction of ultrasonography (US)-guided radiofrequency ablation (RFA) for benign thyroid nodules, and the factors affecting the results obtained. A total of 302 benign thyroid nodules in 236 euthyroid patients underwent RFA between June 2002 and January 2005. RFA was carried out using an internally cooled electrode under local anesthesia. The volume-reduction ratio (VRR) was assessed by US and safety was determined by observing the complications during the follow-up period (1-41 months). The correlation between the VRR and several factors (patient age, volume and composition of the index nodule) was evaluated. The volume of index nodules was 0.11-95.61 ml (mean, 6.13 +/- 9.59 ml). After ablation, the volume of index nodules decreased to 0.00-26.07 ml (mean, 1.12 +/- 2.92 ml) and the VRR was 12.52-100% (mean, 84.11 +/- 14.93%) at the last follow-up. A VRR greater than 50% was observed in 91.06% of nodules, and 27.81% of index nodules disappeared. The complications encountered were pain, hematoma and transient voice changes. In conclusion, RFA is a safe modality effective at reducing volume in benign thyroid nodules.
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MESH
Adolescent, Adult, Aged, Analysis of Variance, *Catheter Ablation, Female, Humans, Male, Middle Aged, Postoperative Complications, Retrospective Studies, Thyroid Nodule/pathology/*surgery/ultrasonography, Treatment Outcome, Ultrasonography, Interventional
링크

주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
After ablation, the volume of index nodules decreased to 0.00–26.07 ml (mean, 1.12 ± 2.92 ml) and the volume-reduction ratio (VRR) was 12.52–100% (mean, 84.11 ± 14.93%) at the last follow-up.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
DOI
10.1007/s00330-008-0880-6.
KCD코드
ICD 03
건강보험코드