Cho, J G; Park, H W; Rhew, J Y; Lee, S R; Chung, W K; Park, O Y; Kim, W; Kim, K H; Kang, K T; Lee, S H; Kim, N H; Park, J C; Ahn, Y K; Jeong, M H; Park, J C; Kang, J C
Japanese circulation journal
2001Jan ; 65 ( 1 ) :18-22.
PMID : 11153816
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Cho, J G -
Park, H W -
Rhew, J Y -
Lee, S R -
Chung, W K -
Park, O Y -
Kim, W -
Kim, K H -
Kang, K T -
Lee, S H -
Kim, N H -
Park, J C -
Ahn, Y K -
Jeong, M H -
Park, J C -
Kang, J C -
ABSTRACT
In Western countries, sudden cardiac death (SCD) is closely related to coronary artery disease, but in Korea the clinical characteristics of SCD are not well determined. Over a 4-year period (June 1995 to May 1999), 186 cases of SCD, ranging in age from 16 to 75 years, were admitted to the Chonnam National University Hospital. In 82 (44.1%) of these, neither symptoms nor evidence of structural heart disease was found and so their clinical characteristics were investigated. There were 66 (80.5%) men and 16 (19.5%) women (male/female ratio = 4.1:1). The mean age was 50 +/- 14 years: 19 (23.2%) were in their 40s, 21 (25.6%) in their 50s, and 17 (20.7%) in their 60s. The time of circulatory collapse witnessed in 68 cases of SCD showed 2 peaks: between midnight and 03.00h (n=16, 23.5%) and between 09.00h and midday (n=15, 22.1%). Unexplained SCD occurred at home in 48 (64.9%) cases and on the street in 12 (16.2%); it occurred during normal daily routine activity in 23 (39.6%) and during sleep in 15 (25.9%). Thirty-three patients (40.2%) experienced various prodromal symptoms, including chest discomfort (n=13, 15.9%) and dyspnea (n=8, 9.8%). The electrocardiogram taken on arrival recorded asystole in 65 (79.3%) and ventricular fibrillation in 17 (20.7%). Idiopathic ventricular fibrillation was diagnosed in 14 (10 men, 4 women; 45 +/- 11 years) of 21 patients who recovered spontaneous circulation. Five (6.1%) patients were discharged alive, and an implantable cardioverter-defibrillator was implanted in 2. Unexplained SCD is common in Korea and develops predominantly in middle-aged males around midnight or in the late morning usually with no prodromal symptoms (59.8%). Idiopathic ventricular fibrillation is thought to be one of the important causes.
Idiopathic ventricular fibrillation, Unexplained sudden cardiac death
MESH
Adolescent, Adult, Circadian Rhythm/physiology, Death, Sudden, Cardiac/epidemiology/*etiology, Electrocardiography, Female, Human Activities, Humans, Korea/epidemiology, Male, Middle Aged, Retrospective Studies, Ventricular Fibrillation/complications
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