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A Case Report of Abducens Nerve Palsy after Cancer Immunotherapy Treated with Korean Medicine

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±èÀçÈ£(Kim Jae-Ho) - Kyung Hee University Hospital at Gangdong Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine
°íÇý¿¬(Ko Hye-Yeon) - Kyung Hee University Hospital at Gangdong Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine
±è¹ÎÈñ(Kim Min-Hee) - Kyung Hee University Hospital at Gangdong Department of Ophthalmology, Otolaryngology and Dermatology of Korean Medicine

Abstract

Objective : The purpose of this study is to report the effect of Korean medicine treatments of abducens nerve palsy after cancer immunotherapy.

Methods : A 63-year-old male patient who was suffering hepatocellular carcinoma had left eye abduction restri ction, diplopia, and decreased visual acuity after taking 5th cancer immunotherapy(atezolizumab + bevacizumab).
Western medicine was administered for 3 weeks, but there was no response. The patient was treated with herbal medicine, acupuncture, electroacupuncture, moxibustion and bee venom pharmacoacupuncture for 4 weeks.

Result : The patient¡¯s eye abduction restriction and diplopia were resolved. Visual acuity was improved from NRS(Numerical Rating Scale) 8 to NRS 2. The patient continued immunotherapy and there was no worsening of symptoms. No adverse events were observed.

Conclusions : This study shows that Korean medicine treatments were effective on abducens nerve palsy after cancer immunotherapy.

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Abducens nerve palsy, Cancer immunotherapy, Korean medicine
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