(Goel Harsh) - Dr. B. R. Ambedkar Institute Rotary Cancer Hospital Laboratory Oncology Unit
(Gupta Ishan) - All India Institute of Medical Sciences
(Mourya Meenakshi) - Vardhaman Mahavir Medical College and Safdarjung Hospital Department of Anaesthesia and Intensive Care
(Gill Sukhdeep) - UPMC Hillman Cancer Center
(Chopra Anita) - Dr. B. R. Ambedkar Institute Rotary Cancer Hospital Laboratory Oncology Unit
(Ranjan Amar) - Dr. B. R. Ambedkar Institute Rotary Cancer Hospital Laboratory Oncology Unit
(Rath Goura Kishor) - Dr. B. R. Ambedkar Institute Rotary Cancer Hospital Department of Radiotherapy
(Tanwar Pranay) - Dr. B. R. Ambedkar Institute Rotary Cancer Hospital Laboratory Oncology Unit
Abstract
The coronavirus disease 2019 (COVID-19) has spread worldwide. It is still a pandemic and poses major health problem across the globe. In our review, clinical characteristics and laboratory parameters of COVID-19 patients were compiled systematically, with special reference to pregnant women in order to understand the disease course. An extensive literature search on various scientific databases for relevant manuscripts was conducted, which yielded 7 manuscripts for final analysis. The most common symptoms were fever (85%), cough (70.63%), chest tightness (37.36%), expectoration (33.27%), fatigue (32%), dyspnea (31.95%), and shortness of breath (31.19%), while hemoptysis (1.0%) was the least common. The associated comorbidities were hypertension (21.6%) and diabetes (10.0%). In terms of hematological parameters, lower total leukocyte counts were observed in 65% of cases and biochemical parameters, patients demonstrated elevated levels of albumin (53.72%), lactate dehydrogenase (45.71%), and natriuretic peptide (34.84%); however, total bilirubin was elevated in only 8% of cases. In the acute inflammatory cytokine profile, C-reactive protein (59.0%), tumor necrosis factor (58.0%), erythrocyte sedimentation rate (57.0%), interleukin-2 (IL-2, 54.0%), and IL-6 (52.0%) levels were increased, while prolactin levels (6.5%) were minimally elevated. The recovery rate was approximately 41%, and mortality was about 6.5%. The study also concluded that the clinical symptoms of COVID-19 were similar among pregnant and non-pregnant women. There was no evidence of vertical transmission of COVID-19 infection. This review critically analyzed COVID-19 as a public health hazard in order to help policy makers, health care givers, and primary physicians to promote early diagnosis and prevention.
Å°¿öµå
COVID-19, SARS-CoV-2, 2019-nCoV, Coronavirus
¿ø¹® ¹× ¸µÅ©¾Æ¿ô Á¤º¸
µîÀçÀú³Î Á¤º¸
À¯È¿¼º°á°ú(Recomendation)
This review summarizes the clinical and laboratory parameters of COVID-19 patients; The most common symptoms were fever (85%), cough (70.63%), chest tightness (37.36%), expectoration (33.27%), fatigue (32%), dyspnea (31.95%), and shortness of breath (31.19%), while hemoptysis (1.0%) was the least common. The associated comorbidities were hypertension (21.6%) and diabetes (10.0%); The recovery rate was approximately 41%, and mortality was about 6.5%.