Radiofrequency Ablation of Papillary Thyroid Microcarcinoma: A 10-Year Follow-Up Study

대한영상의학회지 2021년 82권 4호 p.914 ~ p.922

서유경(Seo Yoo-Kyeong) - Kangwon National University Hospital Department of Radiology
조성휘(Cho Seong-Whi) - Kangwon National University Hospital Department of Radiology
심정석(Sim Jung-Suk) - Withsim Clinic Department of Radiology
양고은(Yang Go-Eun) - Kangwon National University Hospital Department of Radiology
조우진(Cho Woo-Jin) - Withsim Clinic Department of Otolaryngology-Head and Neck Surgery

Abstract

Purpose: To investigate the efficacy and safety of radiofrequency ablation (RFA) for papillary thyroid microcarcinoma (PTMC) after > 10 years of follow-up.

Materials and Methods: This study included five patients who underwent RFA to treat PTMCs (five lesions, mean diameter 0.5 cm, range 0.4-0.7 cm) between November 2006 and December 2009. The inclusion criteria were histopathologically confirmed PTMCs, a single PTMC lesion without extrathyroidal extension, no metastasis, and ineligibility or refusal to undergo surgery. RFA was performed by a single radiologist using a radiofrequency generator and an internally cooled electrode. We retrospectively analyzed the procedure-induced complications, serial changes in ablated tumors, recurrence, and local as well as lymph node metastasis based on data obtained from medical records and radiological images.

Results: The mean follow-up period was 130.6 months (range 121-159 months). Three patients underwent a single RFA session, and two patients underwent two RFA sessions. We observed no procedure-induced complications. Three tumors completely disappeared after ablation, and ablation of the other two tumors resulted in the formation of a small scar that showed long-term stability (mean duration 16.8 months, range 12-27 months). At the last follow-up, no patient showed recurrence or lymph node metastasis, and serum thyroglobulin levels were within normal limits in all patients.

Conclusion: RFA may be effective and safe to treat low-risk PTMC in patients who refuse or are ineligible for surgery.

키워드

Papillary Thyroid Microcarcinoma, Thyroid Neoplasm, Radiofrequency Ablation
원문 및 링크아웃 정보
등재저널 정보
학술진흥재단(KCI) KoreaMed 대한의학회 회원 
주제코드
주제명(Target field)
연구대상(Population)
연구참여(Sample size)
대상성별(Gender)
질병특성(Condition Category)
연구환경(Setting)
연구설계(Study Design)
연구기간(Period)
중재방법(Intervention Type)
중재명칭(Intervention Name)
키워드(Keyword)
유효성결과(Recomendation)
RFA may be effective and safe to treat low-risk PTMC in patients who refuse or are ineligible for surgery.
연구비지원(Fund Source)
근거수준평가(Evidence Hierarchy)
출판년도(Year)
참여저자수(Authors)
대표저자
KCD코드
ICD 03
건강보험코드