À̼ºÇö(Lee Sung-Hyun) - Gachon University Gil Medical Center Department of Pediatrics
±èµ¿¿Ï(Kim Dong-wan) - Gachon University Gil Medical Center Department of Pediatrics
¹é¹Î¿µ(Baek Min-Young) - Gachon University Gachon University Gil Medical Center Department of Internal Medicine
(Tchah Hann) - Gachon University Gil Medical Center Department of Pediatrics
±è¿¬¼±(Kim Yeon-Sun) - Gachon University Gachon University Gil Medical Center Department of Internal Medicine
(Ryoo Eell) - Gachon University Graduate School of Medicine Department of Pediatrics
±èÀ±¹Ì(Kim Yun-Mi) - Gachon University Department of Nursing
Abstract
Purpose: The aim of this study is to evaluate the relationship between abdominal subcutaneous fat thickness meas-ured by ultrasonography (US) and serum lipid profile and liver transaminases in obese children.
Methods: One hundred and sixty-six children diagnosed with obesity from May 2001 to December 2013 were included in this study. Data on serum lipid profile and liver transaminases were collected from clinical records. Abdominal subcutaneous fat thickness and grade of hepatic steatosis were evaluated by US.
Results: Of the 166 children, 107 were diagnosed with hepatic steatosis by US, 46 with grade I, 56 with grade II, and five children with grade III. According to the grade of hepatic steasosis, the average values of midline abdominal subcutaneous fat thickness and right flank abdominal subcutaneous fat thickness measured 2.9¡¾0.8 cm and 1.9¡¾0.7cm in the normal group, 3.3¡¾0.8 cm and 2.0¡¾0.7 cm in grade I, 3.8¡¾0.8 cm and 2.3¡¾0.8 cm in grade II, and 4.1¡¾0.8cm and 2.8¡¾1.4 cm in grade III, respectively. Abdominal subcutaneous fat thickness correlated with grade of hepatic steatosis (p£¼0.01). In addition, abdominal subcutaneous fat thickness correlated with concentration of serum lipids and liver transaminases in the age group of 12-14 years (p£¼0.01).
Conclusion: Abdominal subcutaneous fat thickness measured by US can be used as a reliable predictor of possible hyperlipidemia and steatohepatitis in children, especially during the adolescent stage.
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Child, Obesity, Ultrasonography, Abdominal subcutaneous fat, Hyperlipidemias, Steatohepatitis, Fatty liver
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À¯È¿¼º°á°ú(Recomendation)
Abdominal subcutaneous fat thickness correlated with concentration of serum lipids and liver transaminases in the age group of 12-14 years (p£¼0.01).