Characteristics of Synchronous and Metachronous Multiple Gastric Tumors after Endoscopic Submucosal Dissection of Early Gastric Neoplasm
Clinical Endoscopy 2018³â 51±Ç 3È£ p.266 ~ p.273
ÀÌÇöÁ÷(Lee Hyun-Jik) - Keimyung University School of Medicine Department of Internal Medicine
ÀÌÀ¯Áø(Lee Yoo-Jin) - Keimyung University School of Medicine Department of Internal Medicine
ÀÌÁÖ¿±(Lee Ju-Yup) - Keimyung University School of Medicine Department of Internal Medicine
±èÀº¼ö(Kim Eun-Soo) - Kyungpook National University School of Medicine Department of Internal Medicine
Á¤¿ìÁø(Chung Woo-Jin) - Keimyung University School of Medicine Department of Internal Medicine
À庴±¹(Jang Byoung-Kuk) - Keimyung University School of Medicine Department of Internal Medicine
¹Ú°æ½Ä(Park Kyung-Sik) - Keimyung University School of Medicine Department of Internal Medicine
ȲÀç¼®(Hwang Jae-Seok) - Keimyung University School of Medicine Department of Internal Medicine
Á¶±¤¹ü(Cho Kwang-Bum) - Keimyung University School of Medicine Department of Internal Medicine
Abstract
Background/Aims: Endoscopic submucosal dissection (ESD) has been widely accepted as a method of treatment of early gastric tumor. This study aimed to identify the incidence and characteristics of multiple gastric tumors after ESD.
Methods: Patients with early gastric tumors who were treated by ESD from January 2004 to June 2012 and followed up with endoscopic examination periodically for at least 1 year were enrolled. All multiple gastric lesions were subsequently treated with ESD and the medical records of the patients were retrospectively reviewed.
Results: In total, 643 patients were included. The mean duration of endoscopic follow-up was 45.27¡¾27.59 (range, 12?148) months. Overall, 144 patients (22.4%) showed multiple gastric tumors during the follow-up period (44 synchronous [6.8%] and 100 metachronous [15.5%]). The cumulative incidence rate steadily increased during the follow-up period. More than 50% of the tumors that developed at the same longitudinal location of the stomach were of the same macroscopic and histological type as the primary lesions.
Conclusions: Because synchronous and/or metachronous gastric tumors are common, considerable attention should be paid to detect multiple gastric lesions after ESD of early gastric neoplasm.
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Stomach neoplasms, Endoscopic submucosal dissection, Neoplasms, second primary
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Considerable attention should be paid to detect multiple gastric lesions after ESD of early gastric neoplasm, because synchronous and/or metachronous gastric tumors are common,