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Use of Convalescent Plasma Therapy in Two COVID-19 Patients with Acute Respiratory Distress Syndrome in Korea

Journal of Korean Medical Science 2020년 35권 14호 p.149 ~ p.149

안진영(Ahn Jin-Young) - Yonsei University College of Medicine Severance Hospital Department of Internal Medicine
손유진(Sohn Yu-Jin) - Yonsei University College of Medicine Severance Hospital Department of Internal Medicine
이수환(Lee Su-Hwan) - Yonsei University College of Medicine Severance Hospital Department of Internal Medicine
조윤숙(Cho Yun-Suk) - Yonsei University College of Medicine Severance Hospital Department of Internal Medicine
현종훈(Hyun Jong-Hoon) - Yonsei University College of Medicine Severance Hospital Department of Internal Medicine
백예지(Baek Yae-Jee) - Yonsei University College of Medicine Severance Hospital Department of Internal Medicine
정수진(Jeong Su-Jin) - Yonsei University College of Medicine Severance Hospital Department of Internal Medicine
김정호(Kim Jung-Ho) - Yonsei University College of Medicine Severance Hospital Department of Internal Medicine
구남수(Ku Nam-Su) - Yonsei University College of Medicine Severance Hospital Department of Internal Medicine
염준섭(Yeom Joon-Sup) - Yonsei University College of Medicine Severance Hospital Department of Internal Medicine
노주혜(Roh Ju-Hye) - Yonsei University College of Medicine Severance Hospital Department of Laboratory Medicine
안미영(Ahn Mi-Young) - Seoul Medical Center Department of Internal Medicine
진범식(Chin Bum-Sik) - National Medical Center Department of Internal Medicine
김영삼(Kim Young-Sam) - Yonsei University College of Medicine Severance Hospital Department of Internal Medicine
이혁민(Lee Hyuk-Min) - Yonsei University College of Medicine Severance Hospital Department of Laboratory Medicine
용동은(Yong Dong-Eun) - Yonsei University College of Medicine Severance Hospital Department of Laboratory Medicine
김현옥(Kim Hyun-Ok) - Yonsei University College of Medicine Severance Hospital Department of Laboratory Medicine
김신영(Kim Sin-Young) - Yonsei University College of Medicine Severance Hospital Department of Laboratory Medicine
최준용(Choi Jun-Yong) - Yonsei University College of Medicine Severance Hospital Department of Internal Medicine

Abstract

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 not yet has established its treatment, but convalescent plasma has been expected to increase survival rates as in the case with other emerging viral infections. We describe two cases of COVID-19 treated with convalescent plasma infusion. Both patients presented severe pneumonia with acute respiratory distress syndrome and showed a favorable outcome after the use of convalescent plasma in addition to systemic corticosteroid. To our knowledge, this is the first report of the use of convalescent plasma therapy for COVID-19 in Korea.