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A Case of Localized Amyloid Light-Chain Amyloidosis in the Small Intestine

Intestinal Research
2014년 12권 3호 p.245 ~ p.250
 ( Choi Jong-Hyo ) - Soonchunhyang University College of Medicine Department of Internal Medicine Digestive Disease Center and Research Institute

 ( Ko Bong-Min ) - Soonchunhyang University College of Medicine Department of Internal Medicine Digestive Disease Center and Research Institute
 ( Kim Cheol ) - Soonchunhyang University College of Medicine Department of Internal Medicine Digestive Disease Center and Research Institute
 ( Kim Hee-Kyung ) - Soonchunhyang University College of Medicine Department of Pathology
 ( Han Jae-Pil ) - Soonchunhyang University College of Medicine Department of Internal Medicine Digestive Disease Center and Research Institute
 ( Hong Su-Jin ) - Soonchunhyang University College of Medicine Department of Internal Medicine Digestive Disease Center and Research Institute
 ( Moon Jong-Ho ) - Soonchunhyang University College of Medicine Department of Internal Medicine Digestive Disease Center and Research Institute
 ( Lee Moon-Sung ) - Soonchunhyang University College of Medicine Department of Internal Medicine Digestive Disease Center and Research Institute

Abstract

Amyloidosis is characterized by the abnormal deposition of extracellular amyloid fibrils. Cases involving amyloid light-chain amyloidosis in the small intestine have been reported infrequently in Korea. Here, we report a case of localized light chain protein amyloidosis in the small intestine. Esophagogastroduodenoscopy, push enteroscopy, and capsule endoscopy revealed submucosal tumor-like lesions, multiple shallow ulcers, and several erosions in the distal duodenum and jejunum. An endoscopic biopsy established the diagnosis of amyloidosis. In through an immunohistochemical analysis, the presence of lambda light chain protein was detected. The patient had no evidence of an underlying clonal plasma cell disorder or additional organ involvement. Therefore, we concluded that the patient had localized amyloidosis of the small intestine. (Intest Res 2014;12:245-250)

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학술진흥재단(KCI) KoreaMed 대한의학회 회원 
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